Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intelligence01:27

Intelligence

8.9K
The term "intelligence" is complex because it refers to both behavior and individuals, and its interpretation varies across cultures. European Americans tend to link intelligence with reasoning and cognitive skills, while in Kenya, it is tied to responsible participation in family and social life. In Uganda, intelligence is seen as the ability to know the right actions and carry them out effectively, while the Iatmul people of Papua New Guinea associate it with the capacity to remember...
8.9K
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

250
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
250
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

615
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
615
Preclinical Development: Overview01:28

Preclinical Development: Overview

6.2K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
6.2K
Drug Discovery: Overview01:26

Drug Discovery: Overview

12.4K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
12.4K
Pharmacovigilance01:19

Pharmacovigilance

1.9K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Micronucleus quantification from whole-slide haematology images using AI serves as a translatable pharmacodynamic biomarker for DNA damage response inhibitors.

Scientific reports·2026
Same author

Immunocompetent cell targeting by food-additive titanium dioxide.

Nature communications·2025
Same author

A patent review of von Hippel-Lindau (VHL)-recruiting chemical matter: E3 ligase ligands for PROTACs and targeted protein degradation (2019-present).

Expert opinion on therapeutic patents·2025
Same author

Label-free cell segmentation of diverse lymphoid tissues in 2D and 3D.

Cell reports methods·2023
Same author

Direct, Late-Stage Mono-N-arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites.

ChemMedChem·2021
Same author

Image-Based Cell Profiling Enables Quantitative Tissue Microscopy in Gastroenterology.

Cytometry. Part A : the journal of the International Society for Analytical Cytology·2020
Same journal

The Athlete Biological Passport: How to Personalize Anti-Doping Testing across an Athlete's Career?

Medicine and sport science·2017
Same journal

Gene and Cell Doping: The New Frontier - Beyond Myth or Reality.

Medicine and sport science·2017
Same journal

How Will the Legal and Sport Environment Influence a Future Code?

Medicine and sport science·2017
Same journal

Conclusion and Perspectives.

Medicine and sport science·2017
Same journal

Integration of the Forensic Dimension into Anti-Doping Strategies.

Medicine and sport science·2017
Same journal

Structure and Development of the List of Prohibited Substances and Methods.

Medicine and sport science·2017
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

26.9K

How to Develop Intelligence Gathering in Efficient and Practical Anti-Doping Activities.

Mathieu Holz, Jack Robertson

    Medicine and Sport Science
    |June 2, 2017
    PubMed
    Summary
    This summary is machine-generated.

    The World Anti-Doping Agency (WADA) was established to unify the fight against doping in sports. Its World Anti-Doping Code now includes "nonanalytical" rule violations, emphasizing intelligence gathering to combat doping effectively.

    More Related Videos

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
    10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    10.4K
    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
    09:51

    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

    Published on: September 19, 2025

    535

    Related Experiment Videos

    Last Updated: Mar 1, 2026

    Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
    06:06

    Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

    Published on: February 5, 2018

    26.9K
    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
    10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    10.4K
    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
    09:51

    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

    Published on: September 19, 2025

    535

    Area of Science:

    • Sports Science
    • Criminology
    • International Law

    Background:

    • The fight against doping lacked a unified approach before the World Anti-Doping Agency (WADA).
    • High-profile doping scandals, like the Festina Affair, highlighted the ineffectiveness of fragmented anti-doping efforts.
    • These events spurred the need for a harmonized, international strategy to combat doping in sports.

    Purpose of the Study:

    • To outline the establishment and evolution of WADA.
    • To explain the significance of the World Anti-Doping Code (WADC) in harmonizing anti-doping regulations.
    • To highlight the integration of nonanalytical rule violations and intelligence gathering in modern anti-doping strategies.

    Main Methods:

    • Historical analysis of doping scandals and their impact on policy.
    • Examination of the World Anti-Doping Code (WADC) and its revisions.
    • Review of WADA's framework for rule violations and intelligence gathering.

    Main Results:

    • WADA was established in 1999 to centralize and coordinate global anti-doping efforts.
    • The 2015 WADC introduced "nonanalytical" rule violations, allowing sanctions without positive samples.
    • Intelligence gathering and cooperation with law enforcement are now key components of anti-doping investigations.

    Conclusions:

    • WADA's creation marked a pivotal shift towards a unified global anti-doping stance.
    • "Nonanalytical" rule violations and intelligence gathering represent significant advancements in detecting and deterring doping.
    • The ongoing evolution of anti-doping strategies, as reflected in the WADC, is crucial for maintaining sport integrity.