Related Experiment Video
Updated: Mar 1, 2026
05:13
Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions
Published on: June 21, 2024
1.8K
Selecting embryos with the highest implantation potential using data mining and decision tree based on classical
Beatriz Carrasco1, Gemma Arroyo2, Yolanda Gil2
1Department of Obstetrics, Gynaecology and Reproduction, Instituto Universitario Dexeus, Gran Vía Carles III, 71-75, 08028, Barcelona, Spain. beacar@dexeus.com.
Journal of Assisted Reproduction and Genetics
|June 3, 2017
Summary
Classical embryo morphology and specific time-lapse imaging parameters (t4, t8) on day 3 best predict implantation. This helps select viable embryos for transfer by identifying those with lower implantation potential.
Area of Science:
- Embryology
- Reproductive Medicine
- In Vitro Fertilization (IVF)
Background:
- Selecting viable embryos for transfer is crucial in assisted reproductive technologies.
- Embryonic morphokinetics and morphology are key indicators of developmental potential.
Purpose of the Study:
- To identify embryonic morphokinetic parameters up to Day 3 (D3) that predict implantation.
- To improve embryo selection for transfer in clinical practice using known implantation data (KID).
Main Methods:
- Retrospective analysis of 800 KID embryos cultured with a Time-Lapse system.
- Evaluation of morphokinetic parameters and Day 3 morphology.
Main Results:
- A hierarchical model identified classical morphological score, t4, and t8 as having the best implantation prognosis.
- Classical morphology was the most predictive parameter.
Conclusions:
- Classical morphological score is the primary predictor of implantation.
- Morphokinetics can deselect embryos with lower implantation potential among those with better morphology.
