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Updated: Mar 1, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
The role of myocardial viability in contemporary cardiac practice
Abdelrahman Jamiel1,2, Mohamad Ebid3, Amjad M Ahmed3
1King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Department Mail Code: 1413, P.O. Box 22490, Riyadh, 11426, Kingdom of Saudi Arabia. abdujamiel@yahoo.com.
Insights
Assessing myocardial viability in patients with old myocardial infarction (OMI) is crucial for improving outcomes. Advanced imaging techniques help identify viable myocardium to optimize revascularization strategies.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Ischemic heart disease (IHD) is a leading cause of global mortality.
- Ischemic cardiomyopathy, a consequence of coronary artery disease, significantly impacts patient outcomes.
- Assessing viable myocardium (VM) in old myocardial infarction (OMI) patients is vital for predicting short- and long-term prognosis.
Purpose of the Study:
- To provide a state-of-the-art review on assessing myocardial viability.
- To highlight the importance of preoperative assessment of myocardial viability for guiding revascularization in OMI patients with left ventricular dysfunction.
Main Methods:
- Review of existing observational data and non-invasive imaging techniques for assessing myocardial viability.
- Focus on identifying viable but inadequately perfused myocardium.
Main Results:
- Observational data suggest improved outcomes when revascularization is guided by viability assessment.
- Current cardiovascular imaging faces challenges in precisely assessing myocardial viability.
Conclusions:
- Accurate assessment of myocardial viability is essential for optimizing patient selection for coronary revascularization.
- Further advancements in non-invasive imaging techniques are needed to improve the assessment of myocardial viability.
Abstract:
Ischemic heart disease (IHD) remains the single most common cause of death worldwide. Ischemic cardiomyopathy is a major sequel of coronary artery disease. The economic health burden of IHD is substantial. In patients with old myocardial infarction (OMI), the extent of viable myocardium (VM) directly affects the short- and long-term outcome. There is a considerable collection of observational data showing substantial improvement in patients with significant left ventricular dysfunction when the need for revascularization is guided by preoperative assessment of viability and hibernation. However, a major challenge for present cardiovascular imaging is to identify better ways to assess viable but inadequately perfused myocardium and thus optimize selection of patients for coronary revascularization. Several non-invasive techniques have been developed to detect signs of viability. Hence, our aim is to provide the reader a state-of-the art review for the assessment of myocardial viability.
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