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MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

Lung Cancer Screening

Richard M Hoffman¹, Rolando Sanchez²

¹Department of Medicine, University of Iowa Carver College of Medicine, 200 Hawkins Drive SE 618 GH, Iowa City, IA 52242, USA.

The Medical Clinics of North America

|June 5, 2017

Abstract:

Lung cancer is the leading cause of cancer death in the United States. More than 80% of these deaths are attributed to tobacco use, and primary prevention can effectively reduce the cancer burden. The National Lung Screening Trial showed that low-dose computed tomography (LDCT) screening could reduce lung cancer mortality in high-risk patients by 20% compared with chest radiography. The US Preventive Services Task Force recommends annual LDCT screening for persons aged 55 to 80 years with a 30-pack-year smoking history, either currently smoking or having quit within 15 years.

Keywords:

Decision making Early detection of cancer Lung neoplasms Practice guidelines Tobacco use Tomography, X-ray computed

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