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Orthobiologics in Pediatric Sports Medicine
Christopher C Bray1, Clark M Walker2, David D Spence3
1Pediatric Orthopaedic Surgery and Adolescent Sports Medicine, Department of Orthopaedic Surgery, Steadman Hawkins Clinic of the Carolinas, Greenville Health System, 701 Grove Road, Greenville, SC 29605, USA; University of South Carolina School of Medicine - Greenville, Greenville, SC, USA.
Abstract:
Orthobiologics are biological substances that allow injured muscles, tendons, ligaments, and bone to heal more quickly. They are found naturally in the body; at higher concentrations they can aid in the healing process. These substances include autograft bone, allograft bone, demineralized bone matrix, bone morphogenic proteins, growth factors, stem cells, plasma-rich protein, and ceramic grafts. Their use in sports medicine has exploded in efforts to increase graft incorporation, stimulate healing, and get athletes back to sport with problems including anterior cruciate ligament ruptures, tendon ruptures, cartilage injuries, and fractures. This article reviews orthobiologics and their applications in pediatric sports medicine.
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