The Long-Term Course of Atopic Dermatitis
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Updated: Mar 1, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Katrina Abuabara1, David J Margolis2, Sinéad M Langan3
1Department of Dermatology, University of California San Francisco (UCSF), 2340 Sutter Street, N421, San Francisco, CA 94115, USA.
Abstract:
Atopic dermatitis (AD) is a chronic, relapsing condition, meaning that the intensity of symptoms usually fluctuates over time. Changes in skin physiology may be evident from birth, suggesting that AD may be a lifelong condition marked by intermittent symptoms/disease activity. Methodological considerations for studying the long-term course of AD are reviewed in detail. Improved measurement of the frequency and duration of active disease periods can help to elucidate more about the clinical course AD and the role of treatment in long-term outcomes.
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