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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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Stereotypes, Prejudice, and Discrimination02:55

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Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Epistasis01:39

Epistasis

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In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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Related Experiment Video

Updated: Mar 1, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Atopic Dermatitis: Racial and Ethnic Differences.

Adeline Mei-Yen Yong1, Yong-Kwang Tay2

  • 1Department of Dermatology, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.

Dermatologic Clinics
|June 5, 2017
PubMed
Summary
This summary is machine-generated.

Atopic dermatitis (AD), a chronic inflammatory skin condition, affects millions globally. Its prevalence varies by region, with increasing rates in developing nations and a significant economic burden across all age groups.

Keywords:
Atopic dermatitisEczemaEthnicPatternsTrends

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Area of Science:

  • Dermatology
  • Epidemiology
  • Public Health

Background:

  • Atopic dermatitis (AD) is a widespread, chronic inflammatory skin condition.
  • Affects up to 20% of children and 3% of adults globally.
  • Prevalence shows significant international variation.

Purpose of the Study:

  • To summarize the global prevalence and trends of atopic dermatitis.
  • To highlight the economic impact of atopic dermatitis.

Main Methods:

  • Review of epidemiological data on atopic dermatitis prevalence.
  • Analysis of trends in developed and developing countries.
  • Assessment of healthcare economic burden.

Main Results:

  • AD affects approximately 1 in 5 schoolchildren in developed countries.
  • Adult-onset AD is prevalent, impacting 11-13% in some nations.
  • Increasing AD frequency observed in developing countries.

Conclusions:

  • Atopic dermatitis represents a substantial global health challenge.
  • Understanding regional prevalence is crucial for resource allocation.
  • AD imposes a significant healthcare economic burden across all age demographics.