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Updated: Mar 1, 2026
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Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
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A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
Amira Mansour1, Salma Tammam1, Asma Althani2
1Novel Diagnostics & Therapeutics Research Group, Department of Chemistry, School of Sciences & Engineering, The American University in Cairo, New Cairo, Egypt.
Journal of Microbiological Methods
|June 6, 2017
Abstract:
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based FRET system, this assay achieved a sensitivity and specificity of 98.6% and 90% respectively.
Keywords:
16s rDNAFluorescence Resonance Energy TransferGold nanoparticlesIn vitro diagnosisMycobacterium tuberculosis
