Blood Transfusion and Agglutination
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Blood Transfusion
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Updated: Mar 1, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Roy L Tawes1, Thomas B DuVall1
1Peninsula Hospital Medical Center, Burlingame, California.
Early surgical blood salvage faced complications like coagulopathy. By the late 1970s, improved technology enabled safe red blood cell processing, making blood conservation practical.
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