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Updated: Mar 1, 2026

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
Published on: May 16, 2020
Dynamic Cardiomyoplasty
Ignacio Y Christlieb1, George J Magovern1, James A Magovern1
1Allegheny General Hospital, Allegheny-Singer Research Institute and the Medical College of Pennsylvania, Pittsburgh, PA.
Abstract:
On January 8, 1985, Carpentier and his cardiovascular surgery group at the Broussais Hospital were the first to replace diseased human myocardium with a stimulated latissimus dorsi muscle flap. A few months later, Magovern and co-workers at Allegheny General Hospital in Pittsburgh were the first to repair a large left ventricular aneurysm with a latissimus dorsi cardiomyoplasty. Over the past six years, approximately 120 patients have undergone the operation throughout the world.
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