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Updated: Mar 1, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Pharmacologic Prophylaxis for Contrast-Induced Acute Kidney Injury
Anna Toso1, Mario Leoncini1, Mauro Maioli1
1Cardiology Division, Prato Hospital, Prato, Italy.
Abstract:
In the effort to prevent contrast-induced acute kidney injury (CI-AKI), several pharmacologic agents have been tested for their single or combined nephroprotective properties. To date, however, no drug has been officially approved for this aim. This article focuses on the three agents that have been most extensively studied: statins, N-acetylcysteine, and ascorbic acid. Particular attention is paid to the impact of these drugs on the CI-AKI prevention and improved prognosis.
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