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Volume Segmentation and Analysis of Biological Materials Using SuRVoS Super-region Volume Segmentation Workbench
Published on: August 23, 2017
BreakPoint Surveyor: a pipeline for structural variant visualization
Matthew A Wyczalkowski1,2, Kristine M Wylie2,3, Song Cao1,2
1Oncology Division, Department of Medicine.
Summary:
BreakPoint Surveyor (BPS) is a computational pipeline for the discovery, characterization, and visualization of complex genomic rearrangements, such as viral genome integration, in paired-end sequence data. BPS facilitates interpretation of structural variants by merging structural variant breakpoint predictions, gene exon structure, read depth, and RNA-sequencing expression into a single comprehensive figure.
Availability And Implementation:
Source code and sample data freely available for download at https://github.com/ding-lab/BreakPointSurveyor, distributed under the GNU GPLv3 license, implemented in R, Python and BASH scripts, and supported on Unix/Linux/OS X operating systems.
Contact:
lding@wustl.edu.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
