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Effect of dopaminergic drugs on striatal acetylcholine concentration

V H Sethy, D Wenger

The Journal of Pharmacy and Pharmacology

|January 1, 1985

Abstract:

Striatal acetylcholine concentration was determined after administration of varying doses of apomorphine, (+)-PPP and (-)-PPP to rats. (+)-PPP at 3 and 10 mg kg-1 is a dopamine agonist, whereas (-)-PPP at 0.3 and 3 mg kg-1 is a dopamine antagonist in the striatum.

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