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Real-Time Metabolic Detection in Living Cells Using Hyperpolarized 13C NMR
Published on: July 8, 2025
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Hyperpolarized 133Cs is a sensitive probe for real-time monitoring of biophysical environments
M Karlsson1, J H Ardenkjær-Larsen, M H Lerche
1Technical University of Denmark, Department of Electrical Engineering, Center for Hyperpolarization in Magnetic Resonance, Building 349, DK-2800 Kgs Lyngby, Denmark. mhauler@elektro.dtu.dk mkarls@elektro.dtu.dk.
Chemical Communications (Cambridge, England)
|June 7, 2017
Abstract:
133Cs NMR is a valuable tool for non-invasive analysis of biological systems, where chemical shift and relaxation properties report on changes in the physical environment. Hyperpolarization can increase the liquid-state 133Cs NMR signal by several orders of magnitude and allow real-time monitoring of physical changes in cell based systems.
