A case of clear cell sarcoma-A rare malignancy.

Area of Science:

• Oncology
• Pathology
• Surgical Oncology

Background:

• Clear cell sarcoma (CCS) is a rare soft tissue tumor, often misdiagnosed due to similarities with malignant melanoma (MM).
• Immunohistochemical advancements have rendered previous classifications obsolete, yet the true incidence of CCS remains unknown, estimated at less than 1% of all sarcomas.

Purpose of the Study:

• To present a case of clear cell sarcoma (CCS) with initial misdiagnosis.
• To emphasize the importance of accurate and timely diagnosis in managing CCS.
• To discuss the treatment and follow-up of a CCS patient.

Main Methods:

• A case study of a 22-year-old patient with a gluteal mass initially suspected as infection, then malignant melanoma (MM).
• Definitive diagnosis of clear cell sarcoma (CCS) was established post-surgical removal.
• Treatment involved surgical excision with a 2cm margin, followed by PET-CT and sentinel lymph node biopsy.

Main Results:

• The patient underwent successful surgical treatment for clear cell sarcoma (CCS).
• Despite diagnostic delays, PET-CT and sentinel lymph node biopsy revealed no metastasis.
• One-year postoperative follow-up showed no signs of relapse.

Conclusions:

• Accurate and timely diagnosis of clear cell sarcoma (CCS) is crucial.
• Initial misdiagnosis can lead to delays, tumor growth, and potentially impact prognosis.
• Multidisciplinary follow-up is essential for monitoring patients with clear cell sarcoma (CCS).