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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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The Retinoblastoma Gene01:20

The Retinoblastoma Gene

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Updated: Sep 1, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
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A 3D Organotypic Melanoma Spheroid Skin Model

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[Benign skin tumours].

Sinem Saritas1, Hasan Gökcer Tekin2, Trine Høgsberg3

  • 1Plastik- og Brystkirurgi, Aarhus Universitetshospital.

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|August 12, 2022
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Summary
This summary is machine-generated.

General practitioners frequently encounter benign skin tumors, which must be distinguished from skin cancers. When clinical diagnosis is uncertain, a skin biopsy is essential for accurate histopathological examination.

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Benign skin tumors are common in primary care.
  • Distinguishing benign lesions from malignant neoplasms is crucial.

Purpose of the Study:

  • To highlight the importance of differentiating benign skin tumors from malignancies.
  • To emphasize the role of histopathological examination when clinical diagnosis is uncertain.

Main Methods:

  • Clinical assessment based on patient history and features.
  • Skin biopsy (excisional or punch) for histopathological examination when diagnosis is uncertain.

Main Results:

  • Seborrheic keratoses are the most frequent benign skin tumors, with incidence increasing with age.
  • Common benign lesions like melanocytic naevi, acrochordons, and dermatofibromas can mimic malignant neoplasms.

Conclusions:

  • Accurate diagnosis of skin lesions is vital for appropriate patient management.
  • Histopathological examination remains the gold standard for confirming benignancy and ruling out malignancy in ambiguous cases.