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[Infiltrating basal cell carcinoma with perineural growth in a 15-year-old]
Pernille Stine Jepsen1, Mette Wanscher Kjærskov1, Karen Ehlers Coman2
1Organ- og Plastikkirurgisk Afdeling, Sygehus Lillebælt - Vejle.
Ugeskrift for Laeger
|August 7, 2026
Summary
This case report details a rare pediatric basal cell carcinoma (BCC) in a 15-year-old boy. It emphasizes considering skin cancer in young patients with persistent lesions and highlights multidisciplinary care.
Area of Science:
- Oncology
- Dermatology
- Pediatric Medicine
Background:
- Basal cell carcinoma (BCC) is exceptionally rare in children, typically associated with genetic syndromes.
- Persistent skin lesions in pediatric patients warrant a broad differential diagnosis.
Purpose of the Study:
- To report a rare case of basal cell carcinoma (BCC) with perineural invasion in a 15-year-old male without a known genetic predisposition.
- To discuss the management challenges and multidisciplinary approach for pediatric BCC.
Main Methods:
- Surgical excision with re-excision for clear margins.
- Comprehensive genetic testing to rule out hereditary predispositions.
- International consultation for adjuvant therapy recommendations.
Main Results:
- A 15-year-old male presented with cheek BCC and perineural invasion.
- Complete tumor excision was achieved after re-excision.
- Genetic testing showed no pathogenic variants.
- Adjuvant radiotherapy was deferred due to the patient's age and potential long-term morbidity.
Conclusions:
- Pediatric basal cell carcinoma, even without genetic predisposition, requires careful consideration.
- Multidisciplinary team management is crucial for optimizing outcomes in young BCC patients.
- Skin cancer should be included in the differential diagnosis for persistent skin lesions in children.
