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Reinaldo Pierre, Andreina Guisande, Leida Sifontes

    Acta Gastroenterologica Latinoamericana
    |June 8, 2017
    PubMed
    Summary
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    Eosinophilic Esophagitis is a leading cause of esophageal dysfunction in children and a frequent gastrointestinal issue. This study offers evidence-based recommendations for diagnosing and treating this condition.

    Area of Science:

    • Gastroenterology
    • Pediatric Gastroenterology
    • Immunology

    Background:

    • Eosinophilic Esophagitis (EoE) has significantly increased in prevalence over the past two decades.
    • EoE is now a primary cause of esophageal dysfunction in children.
    • It is also linked to food impaction in adolescents and young adults and therapeutic failure in GERD patients.

    Purpose of the Study:

    • To establish evidence-based recommendations for the diagnosis of Eosinophilic Esophagitis.
    • To provide guidelines for the treatment of Eosinophilic Esophagitis.
    • To synthesize current literature on EoE for clinical application.

    Main Methods:

    • Systematic review of the medical literature.
    • Analysis of studies focusing on EoE diagnosis and treatment.

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  • Evidence synthesis for guideline development.

    • Main Results:

    • Eosinophilic Esophagitis is the most common eosinophilic disease of the gastrointestinal tract.
    • Identification of key diagnostic criteria for EoE.
    • Outline of effective therapeutic strategies for EoE.

    Conclusions:

    • Updated recommendations for EoE diagnosis and treatment are crucial for clinical practice.
    • Systematic literature review supports current management approaches.
    • Further research may refine diagnostic and therapeutic protocols for EoE.