CE: Early Intervention in Patients with Poststroke Depression
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Updated: Mar 1, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Gwendolyn M Hamid1, Meredith A MacKenzie
1Gwendolyn M. Hamid is a graduate student in the PhD program at Villanova University College of Nursing, Villanova, PA, where Meredith A. MacKenzie is an assistant professor. Contact author: Gwendolyn M. Hamid, gwendolyn.hamid@villanova.edu. The authors describe off-label uses of antidepressants within this article. The authors and planners have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
: Nearly one-third of stroke survivors experience depression. Poststroke depression is associated with longer hospital stays, poor physical and cognitive recovery, poor quality of life, high caregiver distress, increased risk of recurrent stroke, and higher rates of morbidity and mortality. Poststroke depression, however, often goes unrecognized and untreated because the physical and cognitive repercussions of stroke make it difficult to identify. Nurses are well positioned to recognize poststroke depression, educate patient caregivers, and aid patients who have poststroke depression in their efforts to achieve physical, cognitive, and emotional recovery. This article explains how poststroke depression often manifests, describes associated risk factors, and discusses the screening tools and therapeutic interventions nurses can use to identify and help manage depression in patients following stroke.
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