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Related Concept Videos

Standards of Care II01:19

Standards of Care II

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Nurses bear specific legal responsibilities under several federal statutes, including:
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Arteries of the Head and Neck01:26

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The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
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Veins of Head and Neck01:19

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The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer Vaccines01:30

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Related Experiment Video

Updated: Feb 28, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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NCCN Guidelines Insights: Head and Neck Cancers, Version 2.2017.

David Adelstein, Maura L Gillison, David G Pfister

    Journal of the National Comprehensive Cancer Network : JNCCN
    |June 10, 2017
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    Summary
    This summary is machine-generated.

    The National Comprehensive Cancer Network (NCCN) Guidelines offer updated recommendations for head and neck cancers, addressing human papillomavirus-associated oropharyngeal cancer and new immunotherapy options for advanced cases.

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    Area of Science:

    • Oncology
    • Head and Neck Surgery

    Background:

    • The NCCN Guidelines provide essential treatment recommendations for various head and neck cancers.
    • Current guidelines cover cancers of the lip, oral cavity, pharynx, larynx, sinuses, and salivary glands.
    • Algorithms for occult primary and advanced head and neck cancers are included.

    Purpose of the Study:

    • To summarize recent updates to the NCCN Guidelines for Head and Neck Cancers.
    • To highlight key discussions on human papillomavirus-associated oropharyngeal cancer.
    • To inform about the availability of immunotherapy for recurrent or metastatic head and neck cancer.

    Main Methods:

    • Review and synthesis of NCCN panel discussions.
    • Analysis of recent clinical evidence and treatment outcomes.
    • Development of updated clinical practice guidelines.

    Main Results:

    • Updated recommendations for head and neck cancers.
    • Emphasis on the rising incidence of human papillomavirus-associated oropharyngeal cancer.
    • Inclusion of immunotherapy as a treatment option for recurrent or metastatic disease.

    Conclusions:

    • The NCCN Guidelines provide current, evidence-based recommendations for head and neck cancer management.
    • The guidelines address evolving challenges, including HPV-driven cancers and advanced disease treatment.
    • Clinicians should consider updated recommendations for optimal patient care.