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Updated: Feb 28, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Clinical Characteristics of Autonomic Dysfunction in Hypertensive Patients with Minor Ischemic Stroke.]
Long-Fei Wu1, Qing Yang2, Chun-Yan Liu3
1Department of Cardiology,Bazhong Central Hospital,Bazhong 636000,China.
Objectives:
To investigate clinical characteristics of autonomic dysfunction (AD) in hypertensive patients with minor ischemic stroke (MIS).
Methods:
Sixty hypertensive patients with MIS (observation group) and 60 age-matched hypertensive patients (control group) were recruited in our study.The clinical data of the patients were collected.Autonomic symptoms were accessed using the Scale for Outcomes in Parkinson disease-Autonomic (SCOPA-AUT).Depression was evaluated with Hamilton Depression Scale (HAM-D) .Age,heart beat rate,concomitant diseases,SCOPA-AUT,and HAM-D were analyzed between the two groups.
Results:
Compared with the control group,the observation group showed an increased incidence of orthostatic hypotension,depression,SCOPA-AUT and HAM-D score.Logistic regression showed HAM-D score>8 [standard partial regression coefficent (β)=0.142,odds ratio (OR)=3.251,P=0.009] and age>60 yr.(β=0.180,OR=1.972, P=0.003) were independent risk factors for AD.
Conclusions:
AD is common in hypertensive patients with MIS and depression is probably the potential etiology.
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