Immunocytochemical localization of somatostatin and cholecystokinin in the cat visual cortex

Immunocytochemistry was used to examine the morphology and distribution of cholecystokinin-like and somatostatin-like neurons in areas 17, 18 and 19 of cat visual cortex as a function of lamination. Immunoreactive cells of both peptides were observed in all layers of cat visual cortex. While somatostatin-like cells occurred mainly in layers II + III and VI, cholecystokinin-like cells were observed chiefly in the superficial layers (I + II + III). Somatostatin-like cells displayed morphological features of multipolar and bipolar varieties, and cholecystokinin-like cells displayed morphological features of multipolar and bitufted varieties. Similar results were obtained for all 3 areas.