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Updated: Feb 28, 2026

Intravital Microscopy of the Inguinal Lymph Node
Published on: April 4, 2011
The video endoscopy inguinal lymphadenectomy for vulvar cancer: A pilot study
Angelica Naldini1, Cristiano Rossitto1, Fabio Pacelli2
1Division of Gynecologic Oncology, Department of Women's and Children's Health, "Agostino Gemelli" Foundation University Hospital, Rome, Italy.
Objective:
This prospective pilot study aims to validate feasibility, efficacy and safeness of the innovative technique of video endoscopy inguinal lymphadenectomy (VEIL) and compare it to open inguinal lymphadenectomy (OIL) in the staging and treatment of vulvar cancer (VC).
Material And Methods:
All patients affected by VC suitable for bilateral inguinal-femoral lymphadenectomy were prospectively enrolled and submitted to VEIL on one side and OIL contralaterally, sparing the saphenous vein. The surgical and post-surgical data were collected. Univariate analysis included chi square analysis or Fisher's exact test, when appropriate for categorical variables, and the Student t test and Mann-Whitney test when appropriate for continuous variables.
Results:
Between October 2014 and June 2015 fifteen patients were valuable for the study. Although nodal retrieval was comparable for both procedures, operative time was higher after VEIL. No intraoperative complications were observed in both techniques. Postoperative complications were observed in 3 and 2 cases for OIL and VEIL respectively. One patient needed reoperation after OIL for wound necrosis and infection. According to Campisi's stage, lymphedema resulted significantly to be lower after VEIL (p = 0.024).
Conclusions:
Waiting for larger series and longer follow-up data, the VEIL seems to be feasible allowing a radical removal of inguinal lymph nodes as well as OIL with lower morbidity.
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