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Updated: Feb 28, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Usefulness of three-dimensional echocardiography in the assessment of valvular involvement in Loeffler endocarditis
Carlos M Hernandez1, Mohammed J Arisha2, Amier Ahmad3
1National Medical Center (Siglo XXI), Cardiology Hospital, IMSS, Mexico City, Mexico.
Insights
Loeffler endocarditis, a heart complication of hypereosinophilic syndrome, is better assessed using combined 2D and 3D echocardiography. This case highlights advanced imaging for improved diagnosis and understanding of eosinophilic heart disease.
Area of Science:
- Cardiology
- Hematology
- Medical Imaging
Background:
- Loeffler endocarditis is a severe cardiac manifestation of hypereosinophilic syndrome.
- It involves eosinophilic infiltration of the heart, leading to restrictive cardiomyopathy and valvular dysfunction.
- Early and accurate diagnosis is crucial for patient management.
Abstract:
Loeffler endocarditis is a complication of hypereosinophilic syndrome resulting from eosinophilic infiltration of heart tissue. We report a case of Loeffler endocarditis in which three-dimensional transthoracic and transesophageal echocardiography provided additional information to what was found by two-dimensional transthoracic echocardiography alone. Our case illustrates the usefulness of combined two- and three-dimensional echocardiography in the assessment of Loeffler endocarditis. In addition, a summary of the features of hypereosinophilic syndrome and Loeffler endocarditis is provided in tabular form.
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