Bone tissue bioprinting for craniofacial reconstruction
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Updated: Feb 28, 2026

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
Published on: August 8, 2022
Pallab Datta1, Veli Ozbolat2,3,4, Bugra Ayan2,3
1Center for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, 711103, West Bengal, India.
Abstract:
Craniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications. Biotechnol. Bioeng. 2017;114: 2424-2431. © 2017 Wiley Periodicals, Inc.

