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Updated: Feb 28, 2026

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Bone tissue bioprinting for craniofacial reconstruction.

Pallab Datta1, Veli Ozbolat2,3,4, Bugra Ayan2,3

  • 1Center for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, 711103, West Bengal, India.

Biotechnology and Bioengineering
|June 11, 2017
PubMed
Summary

Bioprinting shows promise for regenerating craniofacial (CF) bone tissue deficits caused by congenital abnormalities, surgery, or trauma. This review analyzes current bioprinting techniques for CF regenerative therapies.

Keywords:
bioprintingbone repaircraniofacial tissueregenerative medicine

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Area of Science:

  • Regenerative Medicine
  • Biotechnology
  • Craniofacial Surgery

Background:

  • Craniofacial (CF) tissues are complex, with patient-specific variations.
  • Major bone tissue deficits result from congenital abnormalities, tumor resection, and trauma.
  • Current surgical reconstruction methods struggle to manage significant CF osseous deficits.

Purpose of the Study:

  • To review the current state of bone tissue bioprinting.
  • To analyze bioprinting techniques applicable to craniofacial (CF) regenerative therapies.

Main Methods:

  • Literature review of bioprinting technologies for bone tissue regeneration.
  • Analysis of existing bioprinting strategies and their potential for CF applications.

Main Results:

  • Bioprinting offers a versatile solution for complex CF tissue engineering.
  • Current bioprinting techniques provide a foundation for developing CF regenerative therapies.

Conclusions:

  • Bioprinting holds significant potential for addressing craniofacial bone deficits.
  • Further adaptation of bioprinting techniques is crucial for successful CF regenerative medicine.