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Related Experiment Video

Updated: Jun 30, 2026

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
10:19

Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

Published on: August 8, 2022

Bioinstructive Orthogonally-crosslinked Ovoprotein Microgels for Modular Bioprinting.

Suihong Liu, Vaibhav Pal, Joseph Christakiran Moses

    Biorxiv : the Preprint Server for Biology
    |June 29, 2026
    PubMed
    Summary
    This summary is machine-generated.

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    We developed an adaptable ovoprotein microgel for bioprinting. This biomaterial supports tissue engineering, promoting vascularization and bone formation for advanced regenerative medicine applications.

    Area of Science:

    • Biomaterials Science
    • Tissue Engineering
    • Regenerative Medicine

    Background:

    • Bioprinting demands advanced biomaterials with structural adaptability and biological instruction.
    • Current materials often lack the necessary combination of printability, mechanical tunability, and bioactivity.

    Purpose of the Study:

    • To establish an ovoprotein-derived microgel platform for modular bioprinting.
    • To create a biomaterial that is structurally adaptive and biologically instructive for tissue regeneration.

    Main Methods:

    • Synthesized methacrylated ovoproteins to form a photoresponsive hydrogel matrix.
    • Utilized endogenous tyrosine chemistry for dityrosine coupling between microgels, creating granular networks.
    • Tested compatibility with digital light processing, extrusion, and aspiration-assisted bioprinting methods.

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    Related Experiment Videos

    Last Updated: Jun 30, 2026

    Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
    10:19

    Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs

    Published on: August 8, 2022

    Protocols of 3D Bioprinting of Gelatin Methacryloyl Hydrogel Based Bioinks
    10:25

    Protocols of 3D Bioprinting of Gelatin Methacryloyl Hydrogel Based Bioinks

    Published on: December 21, 2019

    Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink
    08:34

    Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink

    Published on: April 21, 2016

    Main Results:

    • The ovoprotein microgels exhibited retained proteomic complexity, tunable mechanics, and cell-regulatory biofunction.
    • Formed cohesive, microporous, and autofluorescent granular networks with programmable rheology.
    • Demonstrated successful bioprinting of vascularized constructs and osteogenic tissues with in vitro maturation.

    Conclusions:

    • Ovoprotein microgel-spheroid bioassembly offers an adaptive and bioinstructive strategy for tissue engineering.
    • This platform supports the development of vascularized and mineralized tissue constructs.
    • The approach enables advanced regenerative medicine applications through modular bioprinting.