Mazes of Nrf2 Regulation.

N K Zenkov1, P M Kozhin, A V Chechushkov

  • 1Research Institute of Experimental and Clinical Medicine, Novosibirsk, 630117, Russia. lemen@centercem.ru.

Summary

The Nrf2 transcription factor regulates cellular redox balance but is typically degraded. Autophagy and epigenetic changes can activate Nrf2, potentially increasing resistance to cancer therapies.

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