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A Practical Approach to Supratentorial Brain Malformations: What Radiologists Should Know
Edward Yang1, Winnie C W Chu2, Edward Y Lee1
1Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Radiologic Clinics of North America
|June 12, 2017
Summary
This review offers radiologists a practical guide to identifying and classifying common congenital brain malformations. It covers key imaging features for conditions like holoprosencephaly and gray matter heterotopia.
Area of Science:
- Neuroradiology
- Developmental Neuroscience
- Medical Imaging
Background:
- Congenital brain malformations present diagnostic challenges for general radiologists.
- Accurate recognition, description, and classification are crucial for patient management.
Purpose of the Study:
- To provide a practical imaging and classification approach for common supratentorial brain malformations.
- To aid radiologists in the detection and characterization of these anomalies.
Main Methods:
- Review of embryology and optimal imaging techniques for brain malformations.
- Summary of distinguishing imaging features for major categories of cerebral malformations.
- Discussion of the role of corpus callosum and basal ganglia abnormalities.
Main Results:
- Detailed imaging features are presented for holoprosencephaly, gray matter heterotopia, lissencephaly/pachygyria, focal cortical dysplasia, polymicrogyria, and cobblestone malformation.
- Emphasis on the diagnostic significance of corpus callosum and basal ganglia assessment.
- A structured approach to classification is outlined.
Conclusions:
- This review equips radiologists with essential knowledge for diagnosing congenital supratentorial brain malformations.
- Understanding embryology and imaging nuances improves diagnostic accuracy.
- Systematic evaluation aids in comprehensive characterization and classification.
