Case Report of Cardiac Arrest After Succinylcholine in a Child With Muscle-Eye-Brain Disease

Area of Science:

• Neurology
• Genetics
• Anesthesiology

Background:

• Muscle-eye-brain disease is a rare autosomal recessive disorder.
• It is characterized by congenital muscular dystrophy, ocular abnormalities, and brain malformation.

Purpose of the Study:

• To report a case of intraoperative hyperkalemic cardiac arrest in a child with undiagnosed Muscle-eye-brain disease.
• To suggest preoperative diagnostic markers for patients with potential myopathy.

Main Methods:

• Case report of a patient with Muscle-eye-brain disease.
• Review of intraoperative events and diagnostic procedures.

Main Results:

• A child with undiagnosed Muscle-eye-brain disease experienced hyperkalemic cardiac arrest after succinylcholine administration.
• The diagnosis of Muscle-eye-brain disease was confirmed post-event.

Conclusions:

• Succinylcholine administration can trigger life-threatening hyperkalemic cardiac arrest in patients with Muscle-eye-brain disease.
• Preoperative serum lactate and creatine kinase levels may serve as useful indicators for myopathy in at-risk individuals.