Right ventricular outflow tract obstruction caused by right ventricular fibroma in a 5-month-old infant: a case report
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Updated: Feb 28, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Fuyang Mei1, Bing Zhou1, Yong Cui2
1Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, No. 158 Shangtang Road, Hangzhou, Zhejiang, 310014, People's Republic of China.
Insights
A rare cardiac fibroma in a 5-month-old infant caused severe right ventricular outflow tract obstruction. Surgical resection of this large right ventricle tumor was successfully performed, proving feasible and safe.
Area of Science:
- Pediatric Cardiology
- Cardiac Surgery
- Pediatric Oncology
Background:
- Cardiac fibroma is an exceedingly rare tumor in neonates and infants.
- This case highlights a significant obstruction in the right ventricular outflow tract due to a large fibroma.
Observation:
- A 5-month-old female infant presented with a large right ventricle mass (26 x 22 mm).
- Clinical findings included a harsh S1 sound and a grade IV systolic murmur.
Findings:
- The large cardiac fibroma caused severe right ventricular outflow tract obstruction.
- Surgical resection of the tumor was successfully achieved.
Implications:
- Surgical excision of large cardiac fibromas in infants is a safe and feasible treatment option.
- Early diagnosis and surgical intervention are crucial for managing obstructive cardiac fibromas in pediatric patients.
Background:
Cardiac fibroma is rarely encountered in children, and even more rare in neonates. We herein report a case of a 5-month-old female with severe right ventricular outflow tract obstruction caused by a large right ventricle fibroma that was successfully surgically resected.
Case Presentation:
This report describes the case of a 5-month-old female infant with a large mass measuring 26 × 22 mm in the right ventricle cured successfully with surgery. Physical examination revealed a harsh S1 sound and a grade IV systolic murmur on the left sternal border. Surgical resection was indicated due to severe right ventricular outflow tract obstruction and further follow-up evaluation was uneventful.
Conclusion:
The surgical procedure to excise such a large cardiac fibroma in a 5-month-old infant is feasible and safe.

