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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Investigation on left ventricular multi-directional deformation in patients of hypertension with different LVEF
Huimei Huang1, Qinyun Ruan2, Meiyan Lin1
1Department of Ultrasound, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Insights
In hypertensive patients, left ventricular circumferential strain (SC) significantly impacts left ventricular ejection fraction (LVEF). This study highlights SC as the primary contributor to pump function in hypertension.
Area of Science:
- Cardiology
- Echocardiography
- Hypertension Research
Background:
- Hypertension commonly affects left ventricular (LV) function.
- Assessing myocardial deformation is crucial for understanding hypertensive heart disease.
- Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function.
Purpose of the Study:
- To investigate multi-directional systolic deformation in hypertensive patients with varying LVEF.
- To determine the contribution of different strain parameters to LVEF in hypertension.
Main Methods:
- 123 hypertensive patients were categorized into three groups based on LVEF.
- Two-dimensional strain echocardiography (2DSE) was used to measure LV longitudinal strain (SL), radial strain (SR), and circumferential strain (SC).
Main Results:
- SL decreased progressively across groups (A to C), while SR and SC were reduced in groups B and C.
- All strain parameters correlated with LVEF, with SC showing the strongest correlation (r=-0.82).
- Diastolic E/e ratio increased from group A to C.
Conclusions:
- Multi-directional LV deformation is closely linked to LVEF in hypertensive individuals.
- Circumferential strain (SC) plays a more prominent role in left ventricular pump function than SL or SR in hypertension.
Background:
This study is aimed at investigating myocardial multi-directional systolic deformation in hypertensive with different left ventricular ejection fraction (LVEF), and exploring its contribution to LVEF.
Methods:
One hundred and twenty-three patients with primary hypertension (HT) were divided into group A (LVEF ≥ 55%), group B (45% ≤ LVEF < 50%, or 50% ≤ LVEF < 55% + LVEDVI ≥ 97 ml/m2), and group C (LVEF < 45%). Two-dimensional strain echocardiography (2DSE) including LV longitudinal strain (SL), radial strain (SR) and circumferential strain (SC) were measured.
Results:
SL decreased gradually from group A, B to C (all p < 0.05) while SR and SC were reduced only in group B and C (all p < 0.05). All strain measurements correlated to LVEF, with the strongest correlation in SC (r = -0.82, p < 0.01) and the second in SL (r = -0.76). The diastolic E/e increased from group A, B to C.
Conclusions:
Left ventricular multi-directional deformation correlated well to LVEF in hypertension and particularly SC, indicating that it was SC, not SL or SR, that makes the prominent contribution to left ventricular pump function.
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