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[Effect of preoperative depression on early postoperative cognitive function in laparoscopic colon cancer patients
1Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China.
Abstract:
Objective: To analyze the effect of preoperative depression on early postoperative cognitive function after general anesthesia during laparoscopic colon cancer surgery. Methods: One hundred and fifty ASA Ⅰ-Ⅱ general aneasthesia patients (male70, female 80)from Sir Run Run Shaw Hospital in May of 2015 to April of 2016, aged 50-85, undergoing selective laparoscopic colon cancer patients were included. Evaluated preoperative depression by self-rating depression scale and evaluated postoperative cognitive function on 1, 3, 7 days by post-operative quality recovery scale. Use the multi-factor logistic regression to select the risk factors. Results: There were 115 (76.7%) patients occurred poor cognitive function. According to SDS, The results of logistic regression analysis showed that the risk factors for postoperative poor cognitive function was severe depression(OR 1.295, 95% CI 1.012-13.184, P=0.048). Conclusion: Preoperative severe depression is a risk factor on postoperative cognitive function in laparoscopic colon cancer patients during general anesthesia.
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