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[Reproducibility and comparison study of two methods evaluating the optic nerve subarachnoid space sectional area
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing 100730, China.
Summary
An optimized method for measuring the optic nerve subarachnoid space (ONSAS) provides higher quality images and improved repeatability compared to traditional techniques. This new approach enhances ONSAS parameter acquisition for better diagnostic accuracy.
Area of Science:
- Ophthalmology and Neuroscience
- Medical Imaging and Diagnostics
Background:
- Accurate measurement of the optic nerve subarachnoid space (ONSAS) is crucial for diagnosing various ophthalmic conditions.
- Traditional methods for ONSAS parameter acquisition have limitations in image quality and repeatability.
Purpose of the Study:
- To optimize the method for acquiring ONSAS parameters, specifically the sectional area.
- To evaluate the repeatability of the optimized ONSAS measurement method compared to the traditional approach.
Main Methods:
- A cross-sectional study involving 10 healthy volunteers (20 eyes) underwent two MRI scans one week apart.
- Both optimized and traditional methods for ONSAS sectional area acquisition were applied and compared.
- Image quality, ONSAS area measurements at different points behind the eyeball, and inter-observer/inter-scan reliability (ICC) were analyzed.
Main Results:
- The optimized method yielded a higher rate of high-quality images (100%, 83%, 78%) compared to the traditional method (80%, 78%, 70%).
- Significantly larger ONSAS areas were measured with the optimized method at 9 mm (P=0.048) and 15 mm (P=0.026) behind the eyeball.
- The optimized method demonstrated superior inter-scan (ICC: 0.879-0.857 vs 0.741-0.639) and inter-observer (ICC: 0.864-0.894 vs 0.785-0.609) reliability.
Conclusions:
- The optimized method simplifies the acquisition of optic nerve subarachnoid space cross-sectional area.
- This new technique offers enhanced measurement reproducibility compared to the traditional method.
- The optimized ONSAS measurement method shows promise for improved diagnostic applications in ophthalmology.
