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Galactomannan from Antrodia cinnamomea Enhances the Phagocytic Activity of Macrophages
Namal Perera1,2, Feng-Ling Yang, Ching-Ming Chang
1Department of Chemistry, National Tsing-Hua University , Hsinchu, Taiwan.
Organic Letters
|June 14, 2017
Abstract:
Galactomannan with an octasaccharide-repeating unit (ACP) was isolated from Taiwan medicinal mushroom Antrodia cinnamomea, and its chemical structure was determined herein. ACP significantly enhanced the phagocytosis and bactericidal activity of J774A.1 murine macrophages against Escherichia coli, with prospects for developing a new immunomodulatory compound or adjuvant in immunotherapy and vaccination.
