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SnapShot: Immune Checkpoint Inhibitors
Gabriel Abril-Rodriguez1, Antoni Ribas2
1Department of Medicine, Division of Hematology-Oncology, University of California, Los Angeles, CA 90095, USA.
Abstract:
Immunotherapy has changed the landscape of cancer treatment. Checkpoint blockade therapies unleash breaks in the immune system and induce long-lasting responses. However, a significant number of patients do not respond (innate resistance), and a subset progress after responding (acquired resistance). A better understanding of the molecular mechanisms underlying checkpoint blockade therapies will facilitate the design of novel strategies to treat and prevent resistance. To view this SnapShot, open or download the PDF.
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