Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

1.0K
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
1.0K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

1.2K
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
1.2K
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

1.9K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.9K
Bioremediation00:46

Bioremediation

22.6K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
22.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular Interactions of Juvenile and Adult Barnacles at the Polymer Interface.

The journal of physical chemistry. B·2026
Same author

Functional Microbiomes at the Interface: Mediators in Marine Biofouling and Larval Settlement.

International journal of molecular sciences·2026
Same author

Sea anemones extract tin associated with polyvinyl chloride pre-production pellets.

Environmental science. Processes & impacts·2026
Same author

Embryonic exposure to irgarol impacts development and larval and juvenile swimming in zebrafish (<i>Danio rerio</i>).

Biofouling·2026
Same author

Egg Hatching, Peptide Pheromones, and Endoproteinases in Barnacles.

International journal of molecular sciences·2025
Same author

Cyanobacteria fouling in photobioreactors: current status and future perspectives for prevention.

Biofouling·2025

Related Experiment Video

Updated: Feb 28, 2026

Experimental Multiscale Methodology for Predicting Material Fouling Resistance
09:13

Experimental Multiscale Methodology for Predicting Material Fouling Resistance

1.6K

Off the Shelf Fouling Management.

Daniel Rittschof1

  • 1Nicholas School of the Environment, Duke University, Durham, NC 27708, USA. Ritt@duke.edu.

Marine Drugs
|June 15, 2017
PubMed
Summary

Researchers developed an environmentally friendly pharmaceutical for antifouling coatings by simplifying a molecule to disrupt organism metamorphosis and ensure biodegradability, offering a sustainable alternative to persistent biocides.

Area of Science:

  • Marine Biology
  • Environmental Science
  • Pharmaceutical Chemistry

Background:

  • Biofouling poses significant challenges in marine environments, impacting infrastructure and ecosystems.
  • Current fouling management strategies often rely on long-lived, broad-spectrum biocides with adverse environmental and health consequences.

Purpose of the Study:

  • To identify and modify a pharmaceutical compound for use in environmentally benign antifouling coatings.
  • To develop a novel approach to fouling management by designing molecules that perform a function and then degrade.

Main Methods:

  • Utilized a bioassay-directed approach to identify an initial pharmaceutical candidate.
  • Conducted structure-function studies and laboratory/field bioassays to simplify the molecule, removing halogens and aromatic rings.
Keywords:
business modelsconserved pathwaysevolutionary principlesfouling managementmetamorphosispharmaceuticals

More Related Videos

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military
14:17

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

Published on: June 29, 2014

15.1K
Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

827

Related Experiment Videos

Last Updated: Feb 28, 2026

Experimental Multiscale Methodology for Predicting Material Fouling Resistance
09:13

Experimental Multiscale Methodology for Predicting Material Fouling Resistance

1.6K
The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military
14:17

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

Published on: June 29, 2014

15.1K
Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

827
  • Modified the molecule for effective delivery within various coating formulations.

    • Main Results:

    • Identified a simplified pharmacophore that disrupts macrofouling organism metamorphosis.
    • Developed a biodegradable molecule that can be readily broken down by bacteria.
    • Demonstrated successful delivery of the modified molecule in antifouling coatings.

    Conclusions:

    • The research presents a new paradigm for fouling management, emphasizing functional, degradable molecules.
    • This approach offers a sustainable alternative to traditional biocides, mitigating risks to human health, the environment, and food security.