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MULTIPLE EVANESCENT WHITE DOT SYNDROME WITH SUBRETINAL DEPOSITS
Orly Gal-Or1,2,3, John A Sorenson1,2, Sarra Gattoussi1,2
1Vitreous Retina Macula Consultants of New York, New York, New York.
Retinal Cases & Brief Reports
|June 15, 2017
Summary
Transient subretinal deposits can occur in Multiple Evanescent White Dot Syndrome (MEWDS). These deposits, identified by multimodal imaging, may represent debris from damaged photoreceptor outer segments.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Neuro-ophthalmology
Background:
- Multiple Evanescent White Dot Syndrome (MEWDS) is an inflammatory condition affecting the outer retina.
- Understanding the full spectrum of imaging findings in MEWDS is crucial for diagnosis and management.
Observation:
- A case of MEWDS presented with transient subretinal deposits.
- Multimodal imaging, including OCT and autofluorescence, characterized these deposits.
- The deposits showed persistent hyperautofluorescence after photobleaching, unlike acute MEWDS lesions.
Findings:
- Transient subretinal deposits were observed in a patient with MEWDS.
- These deposits correlated with hyperreflective material on OCT and persistent hyperautofluorescence.
- No vascular abnormalities were detected on OCT angiography.
Implications:
- Subretinal deposits may be a previously unrecognized feature of MEWDS.
- The persistent hyperautofluorescence suggests a unique composition, possibly photoreceptor outer segment debris.
- Further research is needed to elucidate the exact nature and clinical significance of these deposits in MEWDS.
