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Murine Superficial Lymph Node Surgery
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Lymph node transfer for refractory infectious sites caused by trauma.

Makoto Mihara1,2, Hisako Hara1, Kazuki Kikuchi2

  • 1Department of Lymphatic and Reconstructive Surgery, Saiseikai Kawaguchi General Hospital, Saitama, Japan.

SAGE Open Medical Case Reports
|June 16, 2017
PubMed
Summary

Lymph node transfer using free flaps can effectively treat refractory infections. This innovative approach aids in wound healing for severe injuries and chronic conditions.

Keywords:
Surgeryinfectionlymph node transferlymphedema

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Area of Science:

  • Immunology
  • Surgical Innovation
  • Wound Healing

Background:

  • Lymph nodes play a crucial role in the immune system.
  • Refractory infections pose significant challenges in wound management.
  • Exploring novel therapeutic strategies for persistent infections is essential.

Observation:

  • Two cases of severe lower extremity injuries with refractory bacterial infections were treated.
  • Lymph node transfer via a superficial circumflex iliac artery perforator free flap was performed in both cases.
  • Minimal debridement was employed, preserving tissue integrity.

Findings:

  • Case 1: A 34-year-old male with a large skin defect and infected tendons experienced complete wound healing without recurrence.
  • Case 2: A 73-year-old male with chronic tibial infection and degeneration showed successful wound closure and healing.
  • Both patients demonstrated positive outcomes following lymph node transfer.

Implications:

  • Lymph node transfer represents a promising therapeutic option for managing complex infectious wounds.
  • This technique may enhance local immune response and promote tissue regeneration.
  • Further research is warranted to explore the full potential of lymph node transfer in treating infections.