Related Experiment Video
Updated: Feb 28, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
[Сlinical and physiological characteristics and therapy asthenic disorders in adolescents girls]
E Yu Rodionova1, L S Chutko1, S Yu Surushkina1
1Institute of Human Brain of Russian Academy of Sciences, St. Petersburg, Russia, Consultative and diagnostic Centre for the children 'Yuventa', St. Petersburg, Russia.
Aim:
To study clinical and psychophysiological characteristics of asthenic disorders in adolescent girls in the aspect of treatment efficacy of cortexin.
Material And Methods:
Seventy-five women, aged 14-17 years, who were diagnosed with neurasthenia (ICD-10 F.48.0), were examined. Conventional neurological examination, a 10-point Visual Analogue Scale, the Multidimensional Fatigue Inventory (MFI-20), the A.M. Vein questionnaire, the Spielberger-Khanin questionnaire and EEG were used.
Results And Conclusion:
The high level of anxiety resulted in the development of autonomic symptoms and cephalgia. The EEG study showed that women with neurasthenia were characterized by lower alpha-rhythm power in the occipital sites compared with healthy peers. Treatment with cortexin improved patient's condition in 80% of cases that was supported by the positive EG dynamics.
Related Concept Videos
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Signs of Puberty
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Nature and Nurture

