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Updated: Feb 28, 2026

Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles
Published on: May 5, 2022
Contractile actuation and dynamical gel assembly of paramagnetic filaments in fast precessing fields
Joshua M Dempster1, Pablo Vázquez-Montejo2, Monica Olvera de la Cruz1,2
1Northwestern University Department of Physics and Astronomy, 2145 Sheridan Road F165, Evanston, Illinois 60208, USA.
Abstract:
Flexible superparamagnetic filaments are studied under the influence of fast precessing magnetic fields using simulations and a continuum approximation analysis. We find that individual filaments can be made to exert controllable tensile forces along the precession axis. These forces are exploited for microscopic actuation. In bulk, the filaments can be rapidly assembled into different configurations whose material properties depend on the field parameters. The precession frequency affects filament aggregation and conformation by changing the net torques on the filament ends. Using a time-dependent precession angle allows considerable freedom in choosing properties for filament aggregates. As an example, we design a field that twists chains together to dynamically assemble a self-healing gel.
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