Related Experiment Video
Updated: Feb 28, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
Published on: April 19, 2024
A new global and comprehensive model for ICU ventilator performances evaluation.
Nicolas S Marjanovic1,2, Agathe De Simone3, Guillaume Jegou3
1Urgences Adultes/SAMU 86, CHU de Poitiers, 86000, Poitiers Cedex, France.
Recent ICU ventilators show similar technical performance but varying ergonomics. Some devices pose a high risk of misusage due to poor usability, highlighting a gap in user-centered design for critical care equipment.
Area of Science:
- Critical Care Engineering
- Biomedical Device Evaluation
- Human Factors in Medicine
Background:
- Evaluating recent intensive care unit (ICU) ventilators is crucial for patient safety and effective treatment.
- A comprehensive assessment requires considering both technical capabilities and user interaction (ergonomics).
Purpose of the Study:
- To globally and comprehensively evaluate recent ICU ventilators.
- To assess both technical performance and ergonomic factors of selected devices.
Main Methods:
- Six ICU ventilators were tested using an automated lung simulating various respiratory conditions (compliance, resistance, leaks, inspiratory effort) and oxygen levels.
- Ergonomics were assessed by 20 physicians using physiological stress response, psychocognitive scales (SUS, NASA-TLX), and task completion.
Main Results:
- Technical performance differences between ventilators were minimal.
- Non-invasive ventilation modes significantly impacted patient-ventilator asynchrony.
- Ergonomic assessments revealed significant usability differences, with some devices showing poor adaptation to user needs.
Conclusions:
- Despite comparable technical specifications, some ICU ventilators demonstrate suboptimal ergonomics.
- Poor ergonomics increase the risk of misusage and highlight the need for improved user-centered design in ventilator development.
Related Concept Videos
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Mechanical Ventilation I: Indication and Settings
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:

