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Brugada Syndrome and Exercise Practice: Current Knowledge, Shortcomings and Open Questions
Giuseppe Mascia1, Elena Arbelo2, Jaime Hernandez-Ojeda2
1Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy.
International Journal of Sports Medicine
|June 19, 2017
Summary
Brugada Syndrome (BrS) patients face unclear exercise risks due to potential ECG changes and autonomic imbalance. This review clarifies diagnostic criteria, genetics, and athletic participation recommendations for BrS.
Area of Science:
- Cardiology
- Genetics
- Sports Medicine
Background:
- Brugada Syndrome (BrS) is a hereditary condition linked to sudden cardiac death (SCD).
- BrS exhibits a circadian pattern of ventricular arrhythmias (VA), predominantly occurring at rest.
- Exercise may exacerbate ECG abnormalities and increase cardiac event risk in BrS patients.
Purpose of the Study:
- To review current knowledge on Brugada Syndrome and exercise.
- To address shortcomings and open questions regarding BrS patients during physical activity.
- To provide specific considerations for athletes with BrS.
Main Methods:
- Literature review of existing studies on Brugada Syndrome and exercise.
- Analysis of diagnostic criteria and differential diagnoses in athletes.
- Examination of genetic factors and autonomic nervous system function during exercise.
Main Results:
- Exercise can potentially worsen ECG abnormalities in BrS patients.
- Enhanced vagal tone in athletes may be a risk factor for BrS.
- The precise risk of exercise for BrS patients remains uncertain.
Conclusions:
- Specific considerations for BrS diagnosis and management in athletes are highlighted.
- The role of genetic basis and autonomic imbalance during exercise requires further investigation.
- Recommendations for athletic participation in BrS patients are discussed.
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