Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

1.7K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
1.7K
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

2.2K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.2K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.3K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.3K
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

8.2K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
8.2K
Olfaction01:25

Olfaction

49.2K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
49.2K
Role of Amygdala in Memory01:16

Role of Amygdala in Memory

1.4K
The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory.

eLife·2026
Same author

Non-invasive Neuromodulation Targeting Approach by Mapping Stimulations and Lesions That Modify Visual Memory.

bioRxiv : the preprint server for biology·2026
Same author

Spatial and semantic memory reorganize a hippocampal long-axis gradient.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Superheating of the Collecting System during Renal Microwave Ablations; Experimental Study Using an Ex Vivo Perfused Kidney Model.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Functional dysconnectivity in breast cancer patients undergoing hormone therapy.

Journal of clinical and experimental neuropsychology·2026
Same author

Effects of Omega-3 Fatty Acid Treatment on Risk for Atrial Fibrillation: An Updated Meta-Analysis of 34 Trials including 114,326 Individuals.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Feb 28, 2026

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
07:14

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Published on: October 21, 2021

4.8K

A Closer Look at the Hippocampus and Memory.

Joel L Voss1, Donna J Bridge1, Neal J Cohen2

  • 1Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Trends in Cognitive Sciences
|June 20, 2017
PubMed
Summary

The hippocampus guides visual exploration by managing online memory demands, integrating memory formation with exploratory viewing for coherent memory building. This challenges traditional views of hippocampal memory function.

Keywords:
episodicexplorationeye-movement trackingfMRIlong-term

More Related Videos

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

17.0K
Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

21.0K

Related Experiment Videos

Last Updated: Feb 28, 2026

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
07:14

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Published on: October 21, 2021

4.8K
Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

17.0K
Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

21.0K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Memory Research

Background:

  • Current hippocampal memory function models overlook the impact of pervasive viewing behaviors.
  • Stimulus complexity affects both hippocampal activity and viewing, confounding associative memory research.
  • Existing interpretations of hippocampal function are often ambiguous due to the interplay between perception, behavior, memory, and brain activity.

Purpose of the Study:

  • To propose a new framework for understanding hippocampal function that incorporates viewing behaviors.
  • To explain the intricate relationship between memory and visual exploration.
  • To reconcile memory formation with exploratory viewing within hippocampal function.

Main Methods:

  • The study proposes a theoretical model, integrating existing findings on hippocampal activity, associative memory, and visual perception.
  • It analyzes the confounding effects of stimulus complexity on viewing and memory demands.
  • It synthesizes evidence to support the role of the hippocampus in memory-guided exploration.

Main Results:

  • Hippocampal activity and associative memory demands correlate with stimulus complexity.
  • Viewing behavior is significantly modulated by stimulus complexity, often confounding memory research.
  • The proposed model suggests the hippocampus supports online memory demands crucial for guiding visual exploration.

Conclusions:

  • The hippocampus plays a critical role in orchestrating memory-guided exploration over time to build coherent memories.
  • This perspective integrates memory formation and exploratory viewing as intertwined processes.
  • Reinterpreting hippocampal function through the lens of memory-guided visual exploration offers a more comprehensive understanding.