Related Experiment Video
Updated: Feb 28, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Perioperative use of angiotensin-converting-enzyme inhibitors and angiotensin receptor antagonists
Luis Mario Vaquero Roncero1, David Sánchez Poveda1, Joaquín José Valdunciel García1
1Service of Anesthesiology, Reanimation and Pain Medicine, Complejo Asistencial Universitario de Salamanca, CAUSA, Spain.
Study Objective:
Clinical repercussions of perioperative treatment with ACEIs/ARBs.
Design:
Systematic review according to PRISMA statement.
Setting:
Perioperative period.
Patients:
29 studies 11 cases/cases series, 12 observational studies and 6 randomized studies.
Measurements:
Arterial blood pressure differences, refractory hypotension, other comorbidities.
Main Results:
The studies show different results regarding the topics measured. They are divided in the results regarding blood pressure, long term morbidities and effects in neuraxial anesthesia.
Conclusions:
Withholding AECI/ARBs on the morning prior to surgery could be recommended as a potentially effective measure, with a low level of evidence, in order to reduce the appearance of hypotension in the perioperative period of non-cardiac surgery.
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