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Discoid Lupus Erythematosus Complicated with Pregnancy-induced Hemophagocytic Syndrome

Hideto Takada1, Naoki Kimura1, Yoko Yoshihashi-Nakazato1

  • 1Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Japan.

Internal Medicine (Tokyo, Japan)
|June 20, 2017
PubMed

A 35-year-old woman with discoid lupus erythematosus (DLE) was admitted at 11 weeks' gestation with a persistent fever. Laboratory studies revealed pancytopenia, elevated liver enzymes, and hyperferritinemia. Bone marrow aspiration confirmed the diagnosis of hemophagocytic syndrome (HPS). She had no findings of infection or active systemic lupus erythematosus. The administration of high-dose corticosteroids resolved the clinical and laboratory findings. She delivered a healthy baby at 35 weeks' gestation. This case suggests that DLE can be a predisposing factor for pregnancy-induced HPS.

Keywords:
discoid lupus erythematosushemophagocytic syndromepregnancysystemic lupus erythematosus

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