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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
647
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
782
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

388
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
388
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

422
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
422
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

658
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
658
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

642
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Related Experiment Video

Updated: Feb 28, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Rheumatoid Vasculitis: A Diminishing Yet Devastating Menace.

Shweta Kishore1, Lisa Maher2,3, Vikas Majithia2,3

  • 1Division of Rheumatology, Department of Medicine, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS, 39216, USA. skishore@umc.edu.

Current Rheumatology Reports
|June 21, 2017
PubMed
Summary
This summary is machine-generated.

Rheumatoid vasculitis (RV), a rare rheumatoid arthritis complication, presents diverse symptoms. Despite decreased incidence due to early recognition and new treatments, RV still has high mortality, requiring prompt management.

Keywords:
Clinical featuresExtra-articular manifestationsInvestigationsPathogenesisRheumatoid vasculitisTreatment

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Area of Science:

  • Rheumatology
  • Immunology
  • Vascular Medicine

Background:

  • Rheumatoid vasculitis (RV) is an uncommon but serious complication of rheumatoid arthritis (RA).
  • It involves necrotizing or leukocytoclastic inflammation of small to medium-sized blood vessels.
  • RV is a significant extra-articular manifestation of RA.

Purpose of the Study:

  • To provide an updated review on the epidemiology of rheumatoid vasculitis.
  • To discuss the pathogenesis, clinical presentation, and management strategies for RV.
  • To highlight the challenges in managing this RA complication.

Main Methods:

  • This is a review article.
  • It synthesizes current literature on rheumatoid vasculitis.
  • Epidemiological data and treatment outcomes are analyzed.

Main Results:

  • RV presentation varies based on affected organs and vessel size, commonly involving skin and peripheral nerves.
  • Incidence has decreased with early diagnosis and advanced therapies (immunosuppressants, biologics).
  • Mortality rates remain high, and treatment consensus is lacking, with ongoing debate on biologic roles.

Conclusions:

  • Rheumatoid vasculitis is a severe manifestation of RA requiring prompt recognition and treatment.
  • Effective management strategies are still evolving.
  • Further research is needed to clarify the role of biologics in RV treatment.