A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of
Kui Wang1, Jian-Hua Cui, Si-Yang Xing
1Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-Organic Hybrid Functional Materials Chemistry (Tianjin Normal University), Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387, P. R. China. hxxywk@mail.tjnu.edu.cn hxxyxsy@mail.tjnu.edu.cn.
Chemical Communications (Cambridge, England)
|June 21, 2017
Abstract:
We have successfully constructed a supramolecular assembly based on the anionic recognition of calixpyridinium for the first time employing native biocompatible polysaccharide hyaluronan as the guest, which showed hyaluronidase-responsive disassembly and temperature-responsive morphological conversion from a nanosphere to a nanosquare upon increasing the temperature.
