[Chronobiological approach to managing an exacerbation of chronic recurrent bacterial cystite]

To investigate the effects of complex therapy with and without phototherapy for an exacerbation of chronic recurrent bacterial cystitis in women at the peaks of chronobiological activity.

The study comprised 60 patients (mean age 30.1+/-5.5 years) with exacerbations of chronic recurrent bacterial cystitis. Patients in the comparison group (n=30) were managed with standard therapy, in the study group (n=30) standard therapy was used concurrently with phototherapy by low-intensity light radiation carried out at the maximum peaks of chronobiological activity. An assessment of the results included estimation of clinical and laboratory outcomes and the chronobiological status of patients in both groups.

The study findings showed that phototherapy at the peaks of patients chronobiological activity icombined with standard treatment resulted in a faster reduction of clinical signs of the disease and desynchronosis.