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Visualization of Ambient Mass Spectrometry with the Use of Schlieren Photography

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Published on: June 20, 2016

Solid Sampling with a Diode Laser for Portable Ambient Mass Spectrometry.

Yeni P Yung¹, Raveendra Wickramasinghe¹, Anu Vaikkinen²

¹Department of Chemistry, University of Illinois at Chicago , Chicago, Illinois 60607, United States.

Analytical Chemistry

|June 21, 2017

Summary

This summary is machine-generated.

Portable diode lasers enable new field sampling methods for mass spectrometry. Laser diode thermal desorption (LDTD) coupled with photoionization (APPI) shows promise for analyzing plant and microbial communities on-site.

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Area of Science:

Analytical Chemistry
Spectroscopy
Biotechnology

Background:

Portable mass spectrometry (MS) requires efficient solid sampling techniques.
Diode lasers offer a low-cost, portable power source for laser-based sampling.
Existing methods may lack portability or require complex sample preparation.

Purpose of the Study:

To implement and evaluate a hand-held diode laser for solid sampling in portable ambient mass spectrometry.
To compare laser diode thermal desorption (LDTD) with laser ablation for solid sample analysis.
To assess the utility of LDTD coupled with atmospheric pressure photoionization (APPI) for in-field applications.

Main Methods:

Utilized a 940 nm pseudocontinuous wave diode laser for portable LDTD.
Employed nanosecond pulsed laser ablation at 2940 nm as a comparison method.
Achieved postionization using atmospheric pressure photoionization (APPI) for both techniques.
Analyzed sage leaves (Salvia officinalis) and Pseudomonas aeruginosa biofilms using a field-deployable quadrupole ion trap MS.

Main Results:

LDTD-APPI and laser ablation atmospheric pressure photoionization (LAAPPI) produced similar mass spectra for both plant and microbial samples.
Demonstrated the feasibility of analyzing complex biological samples with portable MS.
Highlighted the role of low-cost, battery-powered diode lasers in advancing portable MS.

Conclusions:

LDTD-APPI is a viable method for in-field sampling of plant and microbial communities using portable ambient MS.
The development of portable diode lasers significantly enhances the feasibility of field-deployable MS applications.
LDTD can be potentially coupled with other ionization sources for broader solid sample analysis.