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Updated: Feb 28, 2026

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
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EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila

Michiko Sekiya1, Akiko Maruko-Otake2, Stephen Hearn3

  • 1Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.

Developmental Cell
|June 21, 2017
PubMed

Keywords:
DrosophilaEDEMsER stressER-associated degradationERADERAD-enhancing α-mannosidase-like proteinsUPRagingneurodegenerationprotein misfoldingunfolded protein response

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